LAMA_000667600

PPPDE putative peptidase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146568 OG7: OG7_0003062 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000163300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000777800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000543000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000643700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000104800 ⚠
Aminopeptidase I zinc metalloprotease (M18)/M
— OG7
LAMA_000458400 ⚠
Leucine-rich repeat/Leucine Rich repeats (2 c
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000111300 ⚠
MORN repeat, putative
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG7
LAMA_000055700 ⚠
DENN (AEX-3) domain containing protein, putat
— OG7
LAMA_000400200 ⚠
Vacuolar protein sorting-associated protein 3
— OG7
LAMA_000097900 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
LAMA_000253200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— OG7
LAMA_000230100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000201300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000398600 ⚠
Insulinase (Peptidase family M16), putative
— OG7
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000722400 ⚠
Peptidase M16 inactive domain containing prot
— OG7
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000108200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000097400 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000279600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000713100 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000396800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000799000 ⚠
Cys/Met metabolism PLP-dependent enzyme/DegT/
— OG7
LAMA_000214400 ⚠
Cys/Met metabolism PLP-dependent enzyme, puta
— OG7
LAMA_000195600 ⚠
Lipase (class 3), putative
— OG7
LAMA_000261700 ⚠
Ring finger domain containing protein, putati
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000415700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000283700 ⚠
Hydantoinase/oxoprolinase N-terminal region/H
— OG7
LAMA_000397100 ⚠
CHAT domain containing protein, putative
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.