LAMA_000440900

CAF1 family ribonuclease, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102215 OG7: OG7_0005534 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000283700 ⚠
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— Both
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— Both
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— +1 more Both
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— Both
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— Both
LAMA_000174200 ⚠
Domain of unknown function(DUF2779), putative
— OG7
LAMA_000542900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000317300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000398600 ⚠
Insulinase (Peptidase family M16), putative
— OG7
LAMA_000201300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000174400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000111000 ⚠
Putative diphthamide synthesis protein, putat
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000079200 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000318400 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LAMA_000684500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000126100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000556200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000763900 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000245300 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000661300 ⚠
LSM domain containing protein, putative
— Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000159500 ⚠
Exonuclease, putative
— Both
LAMA_000013900 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— Both
LAMA_000320300 ⚠
The ARF-like 2 binding protein BART, putative
— Both
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— Both
LAMA_000061600 ⚠
Poly A polymerase head domain/Probable RNA an
— Both
LAMA_000307700 ⚠
SET domain containing protein, putative
— Both
LAMA_000116800 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— Both
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000286000 ⚠
CDP-alcohol phosphatidyltransferase/Cytidylyl
— OG7
LAMA_000559100 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.