LAMA_000245300

Tubulin-tyrosine ligase family, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_104876 OG7: OG7_0001164 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— OG7
LAMA_000575000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— OG7
LAMA_000399500 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LAMA_000149100 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— OG7
LAMA_000287800 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000336900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000522200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000797200 ⚠
ThiF family/Ubiquitin-activating enzyme E1 fo
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000061400 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000191300 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000604900 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000576100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000578900 ⚠
MCM OB domain/MCM P-loop domain/Magnesium che
— OG7
LAMA_000522100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000369600 ⚠
DnaJ domain/DnaJ C terminal domain containing
— OG7
LAMA_000724100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAMA_000620000 ⚠
DNA ligase N terminus/ATP dependent DNA ligas
— OG7
LAMA_000568300 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000758900 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LAMA_000289500 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000648200 ⚠
HI0933-like protein/Pyridine nucleotide-disul
— OG7
LAMA_000647800 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000428900 ⚠
Beta-lactamase superfamily domain containing
— OG7
LAMA_000027200 ⚠
N-terminal of Par3 and HAL proteins, putative
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000428800 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— OG7
LAMA_000290500 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000072200 ⚠
Rhodanese-like domain/Domain of unknown funct
— OG7
LAMA_000318400 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LAMA_000079200 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LAMA_000046300 ⚠
Methylmalonyl Co-A mutase-associated GTPase M
— OG7
LAMA_000556200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000006900 ⚠
PPIC-type PPIASE domain containing protein, p
— OG7
LAMA_000088300 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000047800 ⚠
TatD related DNase, putative
— OG7
LAMA_000204800 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.