LAMA_000442500

ThiF family/Ubiquitin-activating enzyme active site/Ubiquitin fold domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100444 OG7: OG7_0003530 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000789900 ⚠
hypothetical protein, conserved
— Both
LAMA_000048000 ⚠
Ubiquitin-like domain containing protein, put
— Both
LAMA_000789600 ⚠
hypothetical protein, conserved
— Both
LAMA_000506700 ⚠
NUBPL iron-transfer P-loop NTPase/Anion-trans
— Both
LAMA_000579900 ⚠
NUBPL iron-transfer P-loop NTPase/VirC1 prote
— OG6
LAMA_000402200 ⚠
NUBPL iron-transfer P-loop NTPase/ATPase MipZ
— Both
LAMA_000765700 ⚠
hypothetical protein, conserved
— Both
LAMA_000382900 ⚠
Cytidylyltransferase-like, putative
— Both
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— Both
LAMA_000012300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000399500 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LAMA_000428900 ⚠
Beta-lactamase superfamily domain containing
— Both
LAMA_000428800 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LAMA_000698500 ⚠
ABC transporter, putative
— Both
LAMA_000200400 ⚠
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000774700 ⚠
Proteasome activator pa28 beta subunit, putat
— Both
LAMA_000047800 ⚠
TatD related DNase, putative
— Both
LAMA_000064300 ⚠
Iron only hydrogenase large subunit, C-termin
— Both
LAMA_000095200 ⚠
HEAT repeat, putative
— OG7
LAMA_000162100 ⚠
Alcohol dehydrogenase GroES-like domain/Zinc-
— OG7
LAMA_000665200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000437600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000676700 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000245400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000432300 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000608100 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000522100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000696800 ⚠
Cytosolic carboxypeptidase N-terminal domain/
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000047100 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000070000 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAMA_000488100 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000572400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000669800 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000014200 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000357300 ⚠
Tubulin/FtsZ family, GTPase domain containing
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.