LAMA_000245400

XRN 5'-3' exonuclease N-terminus, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146609 OG7: OG7_0016759 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000070000 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000616300 ⚠
GHMP kinases N terminal domain/GHMP kinases C
— OG7
LAMA_000595900 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000705800 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000696800 ⚠
Cytosolic carboxypeptidase N-terminal domain/
— OG7
LAMA_000347400 ⚠
Cytosolic carboxypeptidase N-terminal domain/
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000653200 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000608100 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000064300 ⚠
Iron only hydrogenase large subunit, C-termin
— OG7
LAMA_000385100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000402200 ⚠
NUBPL iron-transfer P-loop NTPase/ATPase MipZ
— OG7
LAMA_000506700 ⚠
NUBPL iron-transfer P-loop NTPase/Anion-trans
— OG7
LAMA_000153000 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000167900 ⚠
Zinc finger, C3HC4 type (RING finger)/Prokary
— OG7
LAMA_000288600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000150500 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LAMA_000284800 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— OG7
LAMA_000171100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000508300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000775800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000088300 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000493500 ⚠
Predicted ATPase of the ABC class, putative
— OG7
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000540200 ⚠
Mitochondrial RNA binding protein MRP, putati
— OG7
LAMA_000393700 ⚠
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— OG7
LAMA_000442100 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000072200 ⚠
Rhodanese-like domain/Domain of unknown funct
— OG7
LAMA_000184300 ⚠
Isochorismatase family, putative
— OG7
LAMA_000132000 ⚠
Isochorismatase family, putative
— OG7
LAMA_000131800 ⚠
Isochorismatase family, putative
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000064000 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.