LAMA_000740500

Dihydrouridine synthase (Dus), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_104072 OG7: OG7_0002064 208 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 208 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000620000 ⚠
DNA ligase N terminus/ATP dependent DNA ligas
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000592400 ⚠
Histidyl-tRNA synthetase/Anticodon binding do
— OG7
LAMA_000083600 ⚠
SIS domain containing protein, putative
— OG7
LAMA_000070300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000771500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000235800 ⚠
Rad9, putative
— OG7
LAMA_000064300 ⚠
Iron only hydrogenase large subunit, C-termin
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000508300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000016200 ⚠
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG7
LAMA_000107300 ⚠
Thioredoxin-like domain/UDP-glucose:Glycoprot
— OG7
LAMA_000812000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000465900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000088300 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000046300 ⚠
Methylmalonyl Co-A mutase-associated GTPase M
— OG7
LAMA_000236500 ⚠
Transcription factor IIB C-terminal module 1,
— OG7
LAMA_000348100 ⚠
Glycosyl hydrolases family 31, putative
— OG7
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— OG7
LAMA_000652100 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
LAMA_000537300 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000072200 ⚠
Rhodanese-like domain/Domain of unknown funct
— OG7
LAMA_000279900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000442100 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000575000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000572900 ⚠
OB-fold nucleic acid binding domain/Replicati
— OG7
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000367500 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000204800 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
LAMA_000597400 ⚠
Armadillo/beta-catenin-like repeat/Atypical A
— OG7
LAMA_000245400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000538300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000273400 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000514500 ⚠
Cupin-like domain containing protein, putativ
— OG7
LAMA_000604900 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LAMA_000487100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000393700 ⚠
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— OG7
LAMA_000047800 ⚠
TatD related DNase, putative
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000420500 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.