LAMA_000590700

OB-fold nucleic acid binding domain/tRNA synthetases class II (D, K and N), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100778 OG7: OG7_0002299 310 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 310 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000781200 ⚠
TGS domain/Threonyl and Alanyl tRNA synthetas
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— Both
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— Both
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000741600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000237000 ⚠
Endonuclease/Exonuclease/phosphatase family/R
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000502500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000487100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000800400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000501300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000662900 ⚠
PheRS DNA binding domain 1/PheRS DNA binding
— OG7
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000771900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000159500 ⚠
Exonuclease, putative
— OG7
LAMA_000348100 ⚠
Glycosyl hydrolases family 31, putative
— OG7
LAMA_000220700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000147500 ⚠
Putative zinc finger in N-recognin (UBR box),
— OG7
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— OG7
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000367500 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000112500 ⚠
XPC-binding domain/UBA/TS-N domain containing
— OG7
LAMA_000532300 ⚠
hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.