LAMA_000502500

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_134896 OG7: OG7_0037546 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000070300
hypothetical protein, conserved
— Both
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— Both
LAMA_000814500
hypothetical protein, conserved
— Both
LAMA_000787400
Microtubule binding/Kinesin motor domain cont
— Both
LAMA_000589400
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— Both
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000694600
Gar1/Naf1 RNA binding region containing prote
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— Both
LAMA_000432800
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— Both
LAMA_000107300
Thioredoxin-like domain/UDP-glucose:Glycoprot
— Both
LAMA_000393700
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000771900
hypothetical protein, conserved
— Both
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000467600 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000395100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000796100 ⚠
PPR repeat, putative
— OG7
LAMA_000348100 ⚠
Glycosyl hydrolases family 31, putative
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000589800 ⚠
hypothetical protein
— OG7
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000652100
Component of IIS longevity pathway SMK-1, put
— Both
LAMA_000616800
tRNA synthetases class I (I, L, M and V)/tRNA
— Both
LAMA_000597400
Armadillo/beta-catenin-like repeat/Atypical A
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.