LAMA_000589400

Microtubule binding/Kinesin motor domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_110246 OG7: OG7_0000136 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000800400
hypothetical protein, conserved
— OG6
LAMA_000131000
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG6
LAMA_000159500
Exonuclease, putative
— OG6
LAMA_000132900
WD domain, G-beta repeat, putative
— OG6
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG6
LAMA_000292100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000781200
TGS domain/Threonyl and Alanyl tRNA synthetas
— OG6
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG6
LAMA_000747200
Uncharacterized conserved protein H4 (DUF2046
— OG6
LAMA_000662900
PheRS DNA binding domain 1/PheRS DNA binding
— OG6
LAMA_000411500
V-ATPase subunit H, putative
— OG6
LAMA_000501300
hypothetical protein, conserved
— OG6
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— OG6
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG6
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG6
LAMA_000125500
STI1 domain containing protein, putative
— OG6
LAMA_000147500
Putative zinc finger in N-recognin (UBR box),
— OG6
LAMA_000063800
Biotin-requiring enzyme/e3 binding domain/2-o
— OG6
LAMA_000016200
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG6
LAMA_000776200
hypothetical protein, conserved
— OG6
LAMA_000598500
Zinc finger, C3HC4 type (RING finger) contain
— OG6
LAMA_000814500
hypothetical protein, conserved
— OG6
LAMA_000502500
hypothetical protein, conserved
— OG6
LAMA_000474600
Tubulin folding cofactor D C terminal, putati
— OG6
LAMA_000202000
N2,N2-dimethylguanosine tRNA methyltransferas
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000423700
hypothetical protein, conserved
— OG6
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG6
LAMA_000473300
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG6
LAMA_000278400
hypothetical protein, conserved
— OG6
LAMA_000787400
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000423100
tRNA-methyltransferase O, putative
— OG6
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG6
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000505500
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG6
LAMA_000656400
Histone chaperone Rttp106-like, putative
— OG6
LAMA_000337300
ATP synthase (E/31 kDa) subunit, putative
— OG6
LAMA_000415500
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000186300
tRNA synthetases class I (C) catalytic domain
— OG6
LAMA_000381200
Mitochondrial branched-chain alpha-ketoacid d
— OG6
LAMA_000437200
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG6
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG6
LAMA_000760000
ATP synthase alpha/beta family, beta-barrel d
— OG6
LAMA_000747000
Glutaminyl-tRNA synthetase, non-specific RNA
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.