LAMA_000474600

Tubulin folding cofactor D C terminal, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102599 OG7: OG7_0006853 198 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 198 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000132900
WD domain, G-beta repeat, putative
— Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000186300
tRNA synthetases class I (C) catalytic domain
— Both
LAMA_000591800
hypothetical protein, conserved
— Both
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— +2 more Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— +1 more Both
LAMA_000299400
Phe-tRNA synthetase beta subunit B1 domain/B3
— Both
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— +1 more Both
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000661500 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000656400
Histone chaperone Rttp106-like, putative
— Both
LAMA_000337300
ATP synthase (E/31 kDa) subunit, putative
— Both
LAMA_000747200
Uncharacterized conserved protein H4 (DUF2046
— Both
LAMA_000016200
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— Both
LAMA_000063800
Biotin-requiring enzyme/e3 binding domain/2-o
— Both
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG6
LAMA_000147500
Putative zinc finger in N-recognin (UBR box),
— Both
LAMA_000125500
STI1 domain containing protein, putative
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— +2 more Both
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— Both
LAMA_000501300
hypothetical protein, conserved
— Both
LAMA_000800400
hypothetical protein, conserved
— Both
LAMA_000662900
PheRS DNA binding domain 1/PheRS DNA binding
— Both
LAMA_000159500
Exonuclease, putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— +2 more Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.