LAMA_000263200

ATPase family associated with various cellular activities (AAA), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_142131 OG7: OG7_0001167 124 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 124 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000198700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000580100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000699000 ⚠
MutS domain III/MutS family domain IV/MutS do
— OG7
LAMA_000524500 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000798700 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000776400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000719300 ⚠
PPPDE putative peptidase domain/PUB domain/Gl
— OG7
LAMA_000612500 ⚠
Stabilization of polarity axis, putative
— OG7
LAMA_000024700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000513400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000239300 ⚠
MutS domain I/MutS domain III/MutS domain V,
— OG7
LAMA_000104800 ⚠
Aminopeptidase I zinc metalloprotease (M18)/M
— OG7
LAMA_000800300 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000598300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000170800 ⚠
RWD domain/Protein kinase domain containing p
— OG7
LAMA_000745100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000170900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000136800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000299500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000189000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000179600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000295800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000437700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000440300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000151900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— OG7
LAMA_000083500 ⚠
TLD, putative
— OG7
LAMA_000044600 ⚠
TLD, putative
— OG7
LAMA_000326300 ⚠
TLD, putative
— OG7
LAMA_000385500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000230700 ⚠
Ecotin, putative
— OG7
LAMA_000228800 ⚠
Ecotin, putative
— OG7
LAMA_000047100 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000029200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000423700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000156300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000232200 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.