LAMA_000784100

Ubiquitin carboxyl-terminal hydrolase/ICP0-binding domain of Ubiquitin-specific protease 7/Ubiquitin-specific protease C-terminal, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101317 OG7: OG7_0002166 221 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 221 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000050400 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— OG7
LAMA_000797200 ⚠
ThiF family/Ubiquitin-activating enzyme E1 fo
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000572900 ⚠
OB-fold nucleic acid binding domain/Replicati
— OG7
LAMA_000219000 ⚠
Eukaryotic glutathione synthase, ATP binding
— OG7
LAMA_000502900 ⚠
Brix domain containing protein, putative
— OG7
LAMA_000088300 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000069000 ⚠
Sperm-tail PG-rich repeat, putative
— OG7
LAMA_000236100 ⚠
Bacterial NAD-glutamate dehydrogenase/Glutama
— OG7
LAMA_000167100 ⚠
MIF4G domain containing protein, putative
— OG7
LAMA_000201400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000156300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000440400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000719300 ⚠
PPPDE putative peptidase domain/PUB domain/Gl
— OG7
LAMA_000429900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000149400 ⚠
Fibronectin-binding protein A N-terminus (Fbp
— OG7
LAMA_000751300 ⚠
Methyltransferase involved in Williams-Beuren
— OG7
LAMA_000576700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000670900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000538300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000245400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000136800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000152700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000231100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000024700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000639300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000409200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000362800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000248900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000203800 ⚠
RNA polymerases N / 8 kDa subunit, putative
— OG7
LAMA_000023000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000580100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000774700 ⚠
Proteasome activator pa28 beta subunit, putat
— OG7
LAMA_000612500 ⚠
Stabilization of polarity axis, putative
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000362300 ⚠
Adenylate cyclase associated (CAP) N terminal
— OG7
LAMA_000290700 ⚠
Fibrillarin/tRNA methyltransferase complex GC
— OG7
LAMA_000385500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000442100 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.