LAMA_000219000

Eukaryotic glutathione synthase, ATP binding domain/Eukaryotic glutathione synthase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101596 OG7: OG7_0006266 71 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 71 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000113600
hypothetical protein, conserved
— Both
LAMA_000676000 ⚠
Importin repeat, putative
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000014200 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000488100 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000407400 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000357300 ⚠
Tubulin/FtsZ family, GTPase domain containing
— OG7
LAMA_000535800 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LAMA_000311400 ⚠
Ubiquitin family/UBA/TS-N domain containing p
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000200400
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000261900
Probable N6-adenine methyltransferase, putati
— Both
LAMA_000064500
Ankyrin repeat, putative
— Both
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— Both
LAMA_000598300 ⚠
LSM domain containing protein, putative
— Both
LAMA_000007300
Ankyrin repeats (many copies)/Ankyrin repeat/
— OG6
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000321000 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000380400 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000576500 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000774700
Proteasome activator pa28 beta subunit, putat
— Both
LAMA_000571200 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000368600 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000665000 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000502800 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000475400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000306800 ⚠
mRNA capping enzyme, putative
— OG7
LAMA_000242200 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000029600 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— Both
LAMA_000567800
hypothetical protein, conserved
— Both
LAMA_000587400 ⚠
NAD binding domain of 6-phosphogluconate dehy
— Both
LAMA_000446600
hypothetical protein, conserved
— Both
LAMA_000427800 ⚠
Kelch motif containing protein, putative
— Both
LAMA_000811100 ⚠
LSM domain containing protein, putative
— Both
LAMA_000207100
hypothetical protein, conserved
— Both
LAMA_000105400
Variant UBP zinc finger/Zn-finger in ubiquiti
— Both
LAMA_000383300
RWD domain containing protein, putative
— Both
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— Both
LAMA_000029500 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— Both
LAMA_000097100
hypothetical protein, conserved
— Both
LAMA_000095200 ⚠
HEAT repeat, putative
— Both
LAMA_000201400
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.