LAMA_000587400

NAD binding domain of 6-phosphogluconate dehydrogenase/NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101839 OG7: OG7_0002731 203 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 203 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000535800 ⚠
UBA/TS-N domain containing protein, putative
— Both
LAMA_000199900 ⚠
Ubiquitin family, putative
— Both
LAMA_000311400 ⚠
Ubiquitin family/UBA/TS-N domain containing p
— OG7
LAMA_000676700 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000339400 ⚠
Enoyl-CoA hydratase/isomerase, putative
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000539300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000015700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000415200 ⚠
Pentatricopeptide repeat domain/PPR repeat fa
— OG7
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000651000 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000553600 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000547700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000136400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000042600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000050700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000138000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000801600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000228700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000243100 ⚠
Ribosomal protein L17, putative
— OG7
LAMA_000070700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000523900 ⚠
Mitochondrial 28S ribosomal protein S34, puta
— OG7
LAMA_000307500 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000566500 ⚠
Electron transfer flavoprotein domain/Electro
— Both
LAMA_000347400 ⚠
Cytosolic carboxypeptidase N-terminal domain/
— Both
LAMA_000765700 ⚠
hypothetical protein, conserved
— Both
LAMA_000365500 ⚠
hypothetical protein, conserved
— Both
LAMA_000676000 ⚠
Importin repeat, putative
— Both
LAMA_000566800 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— Both
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— Both
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— Both
LAMA_000382900 ⚠
Cytidylyltransferase-like, putative
— Both
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— Both
LAMA_000566200 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000420700 ⚠
SEP domain containing protein, putative
— Both
LAMA_000453000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAMA_000340200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000195000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000200400 ⚠
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000575600 ⚠
Telomere recombination/Putative GTP-binding c
— Both
LAMA_000559800 ⚠
hypothetical protein, conserved
— Both
LAMA_000774700 ⚠
Proteasome activator pa28 beta subunit, putat
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.