LAMA_000457300

Aminotransferase class I and II, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100337 OG7: OG7_0003266 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000505400 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— Both
LAMA_000106000 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— Both
LAMA_000192700 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000335700 ⚠
ATP-grasp domain/CoA-ligase, putative
— Both
LAMA_000120600 ⚠
U-box domain containing protein, putative
— Both
LAMA_000114700 ⚠
Choline/Carnitine o-acyltransferase, putative
— Both
LAMA_000159700 ⚠
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000505600 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— Both
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— Both
LAMA_000575600 ⚠
Telomere recombination/Putative GTP-binding c
— Both
LAMA_000566200 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000498600 ⚠
hypothetical protein, conserved
— Both
LAMA_000491700 ⚠
TAP42-like family, putative
— Both
LAMA_000702600 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000808200 ⚠
Protein of unknown function (DUF2009), putati
— Both
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— OG6
LAMA_000624300 ⚠
Ubiquitin family/Ubiquitin carboxyl-terminal
— Both
LAMA_000499500 ⚠
CoA binding domain/Succinyl-CoA ligase like f
— Both
LAMA_000189200 ⚠
Phosphoglucose isomerase, putative
— Both
LAMA_000005900 ⚠
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000213400 ⚠
Threonine synthase N terminus, putative
— Both
LAMA_000247200 ⚠
Amidohydrolase family, putative
— Both
LAMA_000045900 ⚠
Alcohol dehydrogenase GroES-like domain/Zinc-
— Both
LAMA_000019200 ⚠
NPL4 family, putative
— Both
LAMA_000047900 ⚠
hypothetical protein, conserved
— Both
LAMA_000222100 ⚠
YjeF-related protein N-terminus/Carbohydrate
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000275700 ⚠
Dephospho-CoA kinase, putative
— Both
LAMA_000273900 ⚠
GHMP kinases N terminal domain/Mevalonate 5-d
— Both
LAMA_000342500 ⚠
Protein of unknown function (DUF2009), putati
— Both
LAMA_000346900 ⚠
Proteasome subunit, putative
— Both
LAMA_000453000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAMA_000420700 ⚠
SEP domain containing protein, putative
— Both
LAMA_000724400 ⚠
Transcription factor S-II (TFIIS), putative
— Both
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000763300 ⚠
Adaptin N terminal region/Adaptin C-terminal
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000416400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000079800 ⚠
U-box domain containing protein, putative
— OG7
LAMA_000590600 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000087800 ⚠
Adaptin N terminal region containing protein,
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000396800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.