LAMA_000189200

Phosphoglucose isomerase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100716 OG7: OG7_0004783 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000278000
Aconitase family (aconitate hydratase)/Aconit
— Both
LAMA_000756700
Aldose 1-epimerase, putative
— Both
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000768100
Pyruvate kinase, barrel domain/Pyruvate kinas
— Both
LAMA_000042700 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000475100
Transketolase, thiamine diphosphate binding d
— Both
LAMA_000280100
Citrate synthase, C-terminal domain containin
— Both
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000204500
Adenylosuccinate synthetase, putative
— Both
LAMA_000032500 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000228100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000079800 ⚠
U-box domain containing protein, putative
— OG7
LAMA_000666600 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000669800 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000572400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000125400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000538200
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000503900
Phosphoribosyl transferase domain containing
— Both
LAMA_000291200
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000747400
Amino-transferase class IV, putative
— Both
LAMA_000443600 ⚠
Thiolase, N-terminal domain/Beta-ketoacyl syn
— Both
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— Both
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— Both
LAMA_000566200
WD domain, G-beta repeat, putative
— Both
LAMA_000688100
Glucosamine-6-phosphate isomerases/6-phosphog
— Both
LAMA_000120600 ⚠
U-box domain containing protein, putative
— Both
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
LAMA_000620700
S-adenosylmethionine synthetase, N-terminal d
— Both
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000119300
Amidohydrolase family, putative
— Both
LAMA_000800100
Shikimate / quinate 5-dehydrogenase/3-hydroxy
— Both
LAMA_000288700 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000211300 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.