LAMA_000079800

U-box domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_106815 OG7: OG7_0002548 114 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 114 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000705000 ⚠
Nicotinate phosphoribosyltransferase (NAPRTas
— OG7
LAMA_000574300 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000311700 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000592700 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LAMA_000587400 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000352300 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LAMA_000256500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000418500 ⚠
Glutamine amidotransferase class-I/Peptidase
— OG7
LAMA_000014700 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
LAMA_000575600 ⚠
Telomere recombination/Putative GTP-binding c
— OG7
LAMA_000595600 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000107400 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000520300 ⚠
HEAT repeats/PBS lyase HEAT-like repeat, puta
— OG7
LAMA_000528500 ⚠
Glucosamine-6-phosphate isomerases/6-phosphog
— OG7
LAMA_000133600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000283100 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— OG7
LAMA_000254900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000655000 ⚠
Myristoyl-CoA:protein N-myristoyltransferase,
— OG7
LAMA_000045900 ⚠
Alcohol dehydrogenase GroES-like domain/Zinc-
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000638400 ⚠
Tetrapyrrole (Corrin/Porphyrin) Methylases, p
— OG7
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000590600 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000047900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000724400 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000455700 ⚠
Transcription factor S-II (TFIIS), central do
— OG7
LAMA_000374200 ⚠
Metalloenzyme superfamily/BPG-independent PGA
— OG7
LAMA_000421000 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAMA_000505600 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAMA_000650300 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LAMA_000027900 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LAMA_000247200 ⚠
Amidohydrolase family, putative
— OG7
LAMA_000189200 ⚠
Phosphoglucose isomerase, putative
— OG7
LAMA_000273900 ⚠
GHMP kinases N terminal domain/Mevalonate 5-d
— OG7
LAMA_000416400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000679400 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000383900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000443600 ⚠
Thiolase, N-terminal domain/Beta-ketoacyl syn
— OG7
LAMA_000228100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000498500 ⚠
HpcH/HpaI aldolase/citrate lyase family, puta
— OG7
LAMA_000503900 ⚠
Phosphoribosyl transferase domain containing
— OG7
LAMA_000395100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000183800 ⚠
PITH domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.