LAMA_000183800

PITH domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102988 OG7: OG7_0006444 179 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 179 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000368700
Sucrase/ferredoxin-like, putative
— Both
LAMA_000566800 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— +1 more Both
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— Both
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000283100
UTP--glucose-1-phosphate uridylyltransferase,
— Both
LAMA_000552400 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000311100 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000383900 ⚠
hypothetical protein, conserved
— Both
LAMA_000161300
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000131700 ⚠
Iron/manganese superoxide dismutases, alpha-h
— Both
LAMA_000133600
hypothetical protein, conserved
— Both
LAMA_000097400 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000743900 ⚠
hypothetical protein, conserved
— OG6
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000402000
Phosphoglucomutase/phosphomannomutase, alpha/
— Both
LAMA_000125300
UBA-like domain containing protein, putative
— Both
LAMA_000279600 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000528500 ⚠
Glucosamine-6-phosphate isomerases/6-phosphog
— Both
LAMA_000158600
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000671000 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000695600
hypothetical protein, conserved
— Both
LAMA_000435900
Leucine Rich repeat, putative
— OG6
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000311700 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000314900
eIF-6 family, putative
— Both
LAMA_000633000
Biotin/lipoate A/B protein ligase family, put
— Both
LAMA_000779600 ⚠
Thioredoxin/Glutaredoxin, putative
— Both
LAMA_000120600 ⚠
U-box domain containing protein, putative
— Both
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000681300 ⚠
Iron/manganese superoxide dismutases, alpha-h
— Both
LAMA_000247200
Amidohydrolase family, putative
— Both
LAMA_000222100
YjeF-related protein N-terminus/Carbohydrate
— Both
LAMA_000065100 ⚠
Glutaredoxin, putative
— Both
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000416400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000679400 ⚠
Cid1 family poly A polymerase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.