LAMA_000311700

Elongation factor Tu GTP binding domain/Elongation Factor G, domain II/Elongation factor G, domain IV/Elongation factor G C-terminus, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100770 OG7: OG7_0003018 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000763300 ⚠
Adaptin N terminal region/Adaptin C-terminal
— OG7
LAMA_000314900 ⚠
eIF-6 family, putative
— Both
LAMA_000633000 ⚠
Biotin/lipoate A/B protein ligase family, put
— Both
LAMA_000120600 ⚠
U-box domain containing protein, putative
— Both
LAMA_000159700 ⚠
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000247200 ⚠
Amidohydrolase family, putative
— Both
LAMA_000222100 ⚠
YjeF-related protein N-terminus/Carbohydrate
— Both
LAMA_000552400 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000311100 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000671000 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000566500 ⚠
Electron transfer flavoprotein domain/Electro
— Both
LAMA_000453000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAMA_000420700 ⚠
SEP domain containing protein, putative
— Both
LAMA_000575600 ⚠
Telomere recombination/Putative GTP-binding c
— Both
LAMA_000005900
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000351800 ⚠
Peptidase family M3, putative
— Both
LAMA_000383900 ⚠
hypothetical protein, conserved
— Both
LAMA_000395100 ⚠
hypothetical protein, conserved
— Both
LAMA_000655000 ⚠
Myristoyl-CoA:protein N-myristoyltransferase,
— Both
LAMA_000606300 ⚠
Iron-containing alcohol dehydrogenase, putati
— Both
LAMA_000624300 ⚠
Ubiquitin family/Ubiquitin carboxyl-terminal
— Both
LAMA_000535800 ⚠
UBA/TS-N domain containing protein, putative
— Both
LAMA_000705000 ⚠
Nicotinate phosphoribosyltransferase (NAPRTas
— Both
LAMA_000724400 ⚠
Transcription factor S-II (TFIIS), putative
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000495100 ⚠
hypothetical protein, conserved
— Both
LAMA_000283100 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— Both
LAMA_000183800 ⚠
PITH domain containing protein, putative
— Both
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000429600 ⚠
ChaC-like protein, putative
— OG7
LAMA_000136400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000553600 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000651000 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000040500 ⚠
Peptidase family M3, putative
— OG7
LAMA_000595100 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000517300 ⚠
Peptidase family M3, putative
— OG7
LAMA_000759400 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000141900 ⚠
AAA domain (dynein-related subfamily)/AAA dom
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000590600 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000421000 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAMA_000416400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000027900 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.