LAMA_000590600

Eukaryotic initiation factor 4E, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_106272 OG7: OG7_0002303 192 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 192 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000528500 ⚠
Glucosamine-6-phosphate isomerases/6-phosphog
— OG7
LAMA_000663300 ⚠
Alpha/beta hydrolase family/Serine aminopepti
— OG7
LAMA_000624300 ⚠
Ubiquitin family/Ubiquitin carboxyl-terminal
— OG7
LAMA_000678800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000761200 ⚠
Phosphoglucomutase/phosphomannomutase, alpha/
— OG7
LAMA_000249200 ⚠
Transaldolase/Fructose-6-phosphate aldolase,
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000566800 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000077700 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000592700 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LAMA_000587400 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000352300 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LAMA_000256500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000418500 ⚠
Glutamine amidotransferase class-I/Peptidase
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000575600 ⚠
Telomere recombination/Putative GTP-binding c
— OG7
LAMA_000595600 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000107400 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000520300 ⚠
HEAT repeats/PBS lyase HEAT-like repeat, puta
— OG7
LAMA_000254900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000045900 ⚠
Alcohol dehydrogenase GroES-like domain/Zinc-
— OG7
LAMA_000371900 ⚠
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000638400 ⚠
Tetrapyrrole (Corrin/Porphyrin) Methylases, p
— OG7
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000108200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000574300 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000383900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000679400 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000097400 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000133600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000183800 ⚠
PITH domain containing protein, putative
— OG7
LAMA_000402000 ⚠
Phosphoglucomutase/phosphomannomutase, alpha/
— OG7
LAMA_000395100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000811200 ⚠
CS domain containing protein, putative
— OG7
LAMA_000279600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000125300 ⚠
UBA-like domain containing protein, putative
— OG7
LAMA_000283100 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— OG7
LAMA_000199900 ⚠
Ubiquitin family, putative
— OG7
LAMA_000566200 ⚠
WD domain, G-beta repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.