LAMA_000574300

Elongation factor Tu GTP binding domain/Elongation Factor G, domain II/Elongation factor G C-terminus, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_103657 OG7: OG7_0003018 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000495100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000120600 ⚠
U-box domain containing protein, putative
— OG7
LAMA_000079800 ⚠
U-box domain containing protein, putative
— OG7
LAMA_000159700 ⚠
Isocitrate/isopropylmalate dehydrogenase, put
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000247200 ⚠
Amidohydrolase family, putative
— OG7
LAMA_000222100 ⚠
YjeF-related protein N-terminus/Carbohydrate
— OG7
LAMA_000396800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000592700 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LAMA_000587400 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000352300 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LAMA_000256500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000418500 ⚠
Glutamine amidotransferase class-I/Peptidase
— OG7
LAMA_000014700 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
LAMA_000595100 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000040500 ⚠
Peptidase family M3, putative
— OG7
LAMA_000575600 ⚠
Telomere recombination/Putative GTP-binding c
— OG7
LAMA_000595600 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000517300 ⚠
Peptidase family M3, putative
— OG7
LAMA_000759400 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000351800 ⚠
Peptidase family M3, putative
— OG7
LAMA_000107400 ⚠
Domain of unknown function (DUF4139), putativ
— OG7
LAMA_000520300 ⚠
HEAT repeats/PBS lyase HEAT-like repeat, puta
— OG7
LAMA_000141900 ⚠
AAA domain (dynein-related subfamily)/AAA dom
— OG7
LAMA_000795000 ⚠
Aminotransferase class-V, putative
— OG7
LAMA_000606300 ⚠
Iron-containing alcohol dehydrogenase, putati
— OG7
LAMA_000254900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000283100 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— OG7
LAMA_000771600 ⚠
Enoyl-CoA hydratase/isomerase, putative
— OG7
LAMA_000239700 ⚠
GHMP kinases N terminal domain/GHMP kinases C
— OG7
LAMA_000655000 ⚠
Myristoyl-CoA:protein N-myristoyltransferase,
— OG7
LAMA_000273900 ⚠
GHMP kinases N terminal domain/Mevalonate 5-d
— OG7
LAMA_000768100 ⚠
Pyruvate kinase, barrel domain/Pyruvate kinas
— OG7
LAMA_000199900 ⚠
Ubiquitin family, putative
— OG7
LAMA_000311400 ⚠
Ubiquitin family/UBA/TS-N domain containing p
— OG7
LAMA_000535800 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LAMA_000047900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000383900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000679400 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000416400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000421000 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAMA_000724400 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000455700 ⚠
Transcription factor S-II (TFIIS), central do
— OG7
LAMA_000374200 ⚠
Metalloenzyme superfamily/BPG-independent PGA
— OG7
LAMA_000650300 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LAMA_000027900 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LAMA_000015600 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.