LAMA_000256500

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_148250 OG7: OG7_0051961 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000779600 ⚠
Thioredoxin/Glutaredoxin, putative
— Both
LAMA_000065100 ⚠
Glutaredoxin, putative
— Both
LAMA_000026900 ⚠
Glutaredoxin, putative
— OG7
LAMA_000679400 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000498600
hypothetical protein, conserved
— Both
LAMA_000702600
WD domain, G-beta repeat, putative
— Both
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— Both
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— OG6
LAMA_000681300 ⚠
Iron/manganese superoxide dismutases, alpha-h
— Both
LAMA_000541700 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000624300
Ubiquitin family/Ubiquitin carboxyl-terminal
— Both
LAMA_000005900
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000247200
Amidohydrolase family, putative
— Both
LAMA_000045900
Alcohol dehydrogenase GroES-like domain/Zinc-
— Both
LAMA_000418500
Glutamine amidotransferase class-I/Peptidase
— Both
LAMA_000019200
NPL4 family, putative
— Both
LAMA_000047900
hypothetical protein, conserved
— Both
LAMA_000222100
YjeF-related protein N-terminus/Carbohydrate
— Both
LAMA_000400500
hypothetical protein, conserved
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000275700 ⚠
Dephospho-CoA kinase, putative
— Both
LAMA_000677300
hypothetical protein, conserved
— Both
LAMA_000273900
GHMP kinases N terminal domain/Mevalonate 5-d
— Both
LAMA_000249200
Transaldolase/Fructose-6-phosphate aldolase,
— Both
LAMA_000342500 ⚠
Protein of unknown function (DUF2009), putati
— Both
LAMA_000166400
Phosphorylase superfamily, putative
— Both
LAMA_000552500 ⚠
50S ribosome-binding GTPase/Protein of unknow
— Both
LAMA_000073500 ⚠
Nodulation protein S (NodS)/Methyltransferase
— Both
LAMA_000453000
Alanine racemase, N-terminal domain containin
— Both
LAMA_000051000 ⚠
hypothetical protein, conserved
— Both
LAMA_000724400 ⚠
Transcription factor S-II (TFIIS), putative
— Both
LAMA_000450900
Ran-interacting Mog1 protein, putative
— Both
LAMA_000136400
hypothetical protein, conserved
— OG7
LAMA_000686600 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LAMA_000547000 ⚠
50S ribosome-binding GTPase/Ferrous iron tran
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000108200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000574300 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000553600 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000421000 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000303800 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
Page 1 of 4
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.