LAMA_000541700

WD domain, G-beta repeat, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_103369 OG7: OG7_0003947 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000578200 ⚠
eIF3 subunit 6 N terminal domain/PCI domain c
— OG7
LAMA_000258500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000377800 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
LAMA_000615900 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
LAMA_000308100 ⚠
RNA polymerase I-associated factor PAF67, put
— OG7
LAMA_000271600 ⚠
Eukaryotic translation initiation factor eIF2
— OG7
LAMA_000664300 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000688200 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000408000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000209500 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000377000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000448800 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000805000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000809400 ⚠
Centriolar protein SAS N-terminal, putative
— OG7
LAMA_000676500 ⚠
CSN8/PSMD8/EIF3K family, putative
— OG7
LAMA_000547000 ⚠
50S ribosome-binding GTPase/Ferrous iron tran
— OG7
LAMA_000686600 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LAMA_000489100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000586800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000541800 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000718000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000494200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000300600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000421000 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAMA_000675300 ⚠
Cytidylyltransferase-like, putative
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000026900 ⚠
Glutaredoxin, putative
— OG7
LAMA_000275700 ⚠
Dephospho-CoA kinase, putative
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000505600 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— Both
LAMA_000669900 ⚠
Phosphomannose isomerase type I, putative
— Both
LAMA_000256500 ⚠
hypothetical protein, conserved
— Both
LAMA_000161300
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000131700 ⚠
Iron/manganese superoxide dismutases, alpha-h
— Both
LAMA_000183800 ⚠
PITH domain containing protein, putative
— Both
LAMA_000021500 ⚠
Phosphoglycerate kinase, putative
— Both
LAMA_000164200 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— Both
LAMA_000158600
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000435900
Leucine Rich repeat, putative
— OG6
LAMA_000779600 ⚠
Thioredoxin/Glutaredoxin, putative
— Both
LAMA_000619500 ⚠
PAS fold/Phosphoglycerate kinase, putative
— Both
LAMA_000432700
Dephospho-CoA kinase, putative
— OG6
LAMA_000681300 ⚠
Iron/manganese superoxide dismutases, alpha-h
— Both
LAMA_000400500 ⚠
hypothetical protein, conserved
— Both
LAMA_000065100 ⚠
Glutaredoxin, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.