LAMA_000494200

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147150 OG7: OG7_0043510 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000377800
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000615900
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000711600
hypothetical protein, conserved
— Both
LAMA_000757500
hypothetical protein, conserved
— Both
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— Both
LAMA_000553800
hypothetical protein, conserved
— Both
LAMA_000616100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000773400
hypothetical protein, conserved
— Both
LAMA_000722600 ⚠
hypothetical protein, conserved
— Both
LAMA_000737500
hypothetical protein, conserved
— Both
LAMA_000719200
hypothetical protein, conserved
— Both
LAMA_000665600
hypothetical protein, conserved
— Both
LAMA_000632200
hypothetical protein, conserved
— Both
LAMA_000738700 ⚠
Myosin head (motor domain), putative
— Both
LAMA_000522900
hypothetical protein, conserved
— Both
LAMA_000683600
CS domain containing protein, putative
— Both
LAMA_000377600
hypothetical protein, conserved
— Both
LAMA_000355600
WD domain, G-beta repeat, putative
— Both
LAMA_000766700
WD domain, G-beta repeat/Coatomer WD associat
— Both
LAMA_000116700
hypothetical protein, conserved
— Both
LAMA_000489100
hypothetical protein, conserved
— OG7
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000221400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000693600 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000456400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000127800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000711100 ⚠
Glutathione S-transferase, N-terminal domain/
— OG7
LAMA_000187400 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAMA_000541700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000809900 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
LAMA_000481300
hypothetical protein, conserved
— Both
LAMA_000149700 ⚠
Glutathione S-transferase, N-terminal domain/
— Both
LAMA_000285600 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— Both
LAMA_000300600
hypothetical protein, conserved
— Both
LAMA_000391000
Adaptin N terminal region/Coatomer beta C-ter
— Both
LAMA_000098000
hypothetical protein, conserved
— Both
LAMA_000493800
ER-Golgi trafficking TRAPP I complex 85 kDa s
— Both
LAMA_000578200
eIF3 subunit 6 N terminal domain/PCI domain c
— Both
LAMA_000345700 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000258500
hypothetical protein, conserved
— Both
LAMA_000055300
hypothetical protein, conserved
— Both
LAMA_000300000
hypothetical protein, conserved
— Both
LAMA_000386600
hypothetical protein, conserved
— Both
LAMA_000147700
hypothetical protein, conserved
— Both
LAMA_000521200
hypothetical protein, conserved
— OG6
LAMA_000430300
MORN repeat, putative
— Both
LAMA_000586800
hypothetical protein, conserved
— Both
LAMA_000737300
Calcineurin-like phosphoesterase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.