LAMA_000377600

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146958 OG7: OG7_0037735 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000521400 ⚠
Methyltransferase domain containing protein,
— OG7
LAMA_000187400 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAMA_000711100 ⚠
Glutathione S-transferase, N-terminal domain/
— OG7
LAMA_000753600 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000620400 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000061800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000546300 ⚠
Protein tyrosine kinase/Fungal protein kinase
— OG7
LAMA_000493900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000777200 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000743400 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LAMA_000562000
SNARE associated Golgi protein, putative
— Both
LAMA_000494200
hypothetical protein, conserved
— Both
LAMA_000525000
Zn-finger in Ran binding protein and others/S
— Both
LAMA_000773400
hypothetical protein, conserved
— Both
LAMA_000377800
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000227100
Protein phosphatase 2C, putative
— OG6
LAMA_000624900 ⚠
N-terminal domain of 16S rRNA methyltransfera
— OG7
LAMA_000179100 ⚠
AAA domain (Cdc48 subfamily)/ATPase family as
— OG7
LAMA_000539600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000738700 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000532100 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000610500 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000758100 ⚠
Peroxisome biogenesis factor 1, N-terminal/AT
— OG7
LAMA_000186800
SAC3/GANP family, putative
— OG7
LAMA_000242000 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000108400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000493100 ⚠
PUA domain/16S rRNA methyltransferase RsmB/F,
— OG7
LAMA_000757500
hypothetical protein, conserved
— Both
LAMA_000572100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000321000 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000380400 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000576500 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000571200 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000368600 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000475400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000242200 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000427800 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000391000
Adaptin N terminal region/Coatomer beta C-ter
— Both
LAMA_000386600
hypothetical protein, conserved
— Both
LAMA_000440100
AMP-binding enzyme/AMP-binding enzyme C-termi
— Both
LAMA_000719200
hypothetical protein, conserved
— Both
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— Both
LAMA_000746000
Glycosyl hydrolase family 65 central catalyti
— Both
LAMA_000581500
Adaptin N terminal region/Coatomer gamma subu
— Both
LAMA_000493800
ER-Golgi trafficking TRAPP I complex 85 kDa s
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.