LAMA_000525000

Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146743 OG7: OG7_0043053 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000675300 ⚠
Cytidylyltransferase-like, putative
— Both
LAMA_000275700 ⚠
Dephospho-CoA kinase, putative
— Both
LAMA_000453000
Alanine racemase, N-terminal domain containin
— Both
LAMA_000566500
Electron transfer flavoprotein domain/Electro
— Both
LAMA_000420700
SEP domain containing protein, putative
— Both
LAMA_000575600
Telomere recombination/Putative GTP-binding c
— Both
LAMA_000409400
hypothetical protein, conserved
— Both
LAMA_000464300
AKAP7 2'5' RNA ligase-like domain containing
— Both
LAMA_000005900
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000232600
hypothetical protein, conserved
— Both
LAMA_000624300
Ubiquitin family/Ubiquitin carboxyl-terminal
— Both
LAMA_000790400
hypothetical protein, conserved
— Both
LAMA_000021900 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000581500
Adaptin N terminal region/Coatomer gamma subu
— Both
LAMA_000615900
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000683600
CS domain containing protein, putative
— Both
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000711600
hypothetical protein, conserved
— Both
LAMA_000757500
hypothetical protein, conserved
— Both
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— Both
LAMA_000553800
hypothetical protein, conserved
— Both
LAMA_000616100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000773400
hypothetical protein, conserved
— Both
LAMA_000722600 ⚠
hypothetical protein, conserved
— Both
LAMA_000737500
hypothetical protein, conserved
— Both
LAMA_000719200
hypothetical protein, conserved
— Both
LAMA_000665600
hypothetical protein, conserved
— Both
LAMA_000632200
hypothetical protein, conserved
— Both
LAMA_000738700 ⚠
Myosin head (motor domain), putative
— Both
LAMA_000377800
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000355600
WD domain, G-beta repeat, putative
— Both
LAMA_000377600
hypothetical protein, conserved
— Both
LAMA_000766700
WD domain, G-beta repeat/Coatomer WD associat
— Both
LAMA_000116700
hypothetical protein, conserved
— Both
LAMA_000705000
Nicotinate phosphoribosyltransferase (NAPRTas
— Both
LAMA_000724400 ⚠
Transcription factor S-II (TFIIS), putative
— Both
LAMA_000494200
hypothetical protein, conserved
— Both
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— Both
LAMA_000194900 ⚠
Kinesin motor domain/Microtubule binding/TRAF
— OG7
LAMA_000209000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000026100 ⚠
Kinesin motor domain/Microtubule binding, put
— OG7
LAMA_000626000 ⚠
Microtubule binding/Kinesin motor domain cont
— OG7
LAMA_000136400
hypothetical protein, conserved
— OG7
LAMA_000553600 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000651000 ⚠
Aldo/keto reductase family, putative
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.