LAMA_000615900

Eukaryotic translation initiation factor 3 subunit 7 (eIF-3), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102252 OG7: OG7_0006808 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000271600
Eukaryotic translation initiation factor eIF2
— +2 more Both
LAMA_000345700 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000541700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000308100
RNA polymerase I-associated factor PAF67, put
— Both
LAMA_000750800
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000578200
eIF3 subunit 6 N terminal domain/PCI domain c
— Both
LAMA_000377800
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000494200
hypothetical protein, conserved
— Both
LAMA_000732800
Domain found in IF2B/IF5, putative
— Both
LAMA_000537600 ⚠
Dehydrogenase E1 component/Transketolase, pyr
— Both
LAMA_000341500 ⚠
2-oxoglutarate dehydrogenase N-terminus/Dehyd
— Both
LAMA_000797600 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— Both
LAMA_000014400 ⚠
hypothetical protein
— Both
LAMA_000116700
hypothetical protein, conserved
— Both
LAMA_000232600
hypothetical protein, conserved
— Both
LAMA_000200700
hypothetical protein, conserved
— Both
LAMA_000525000
Zn-finger in Ran binding protein and others/S
— Both
LAMA_000481300
hypothetical protein, conserved
— Both
LAMA_000328100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000129500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000014300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000575700 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000091100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000292500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000157800 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000809900 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000616100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000285600 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— Both
LAMA_000581500
Adaptin N terminal region/Coatomer gamma subu
— Both
LAMA_000591900
Domain of unknown function (DUF382)/PSP, puta
— Both
LAMA_000055300
hypothetical protein, conserved
— Both
LAMA_000258500
hypothetical protein, conserved
— Both
LAMA_000021900 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000683600
CS domain containing protein, putative
— Both
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— Both
LAMA_000113700
hypothetical protein, conserved
— Both
LAMA_000773400
hypothetical protein, conserved
— Both
LAMA_000665600
hypothetical protein, conserved
— Both
LAMA_000676500
CSN8/PSMD8/EIF3K family, putative
— Both
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
LAMA_000632200
hypothetical protein, conserved
— Both
LAMA_000440400
hypothetical protein, conserved
— Both
LAMA_000466300
Translation initiation factor SUI1, putative
— Both
LAMA_000430300
MORN repeat, putative
— Both
LAMA_000097100
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.