LAMA_000537600

Dehydrogenase E1 component/Transketolase, pyrimidine binding domain/2-oxoglutarate dehydrogenase C-terminal, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100311 OG7: OG7_0003220 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000332600 ⚠
Biotin-requiring enzyme/e3 binding domain/2-o
— OG7
LAMA_000615900 ⚠
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000315400 ⚠
Ribosomal protein S13/S18, putative
— Both
LAMA_000025000 ⚠
Ribosomal protein S13/S18, putative
— Both
LAMA_000715900 ⚠
Ribosomal protein L37e, putative
— Both
LAMA_000325900 ⚠
Ribosomal L37ae protein family, putative
— Both
LAMA_000495400 ⚠
Transketolase, pyrimidine binding domain/Tran
— Both
LAMA_000341500 ⚠
2-oxoglutarate dehydrogenase N-terminus/Dehyd
— Both
LAMA_000518200 ⚠
hypothetical protein, conserved
— Both
LAMA_000554300 ⚠
Prp19/Pso4-like/WD domain, G-beta repeat, put
— Both
LAMA_000627000 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000732800 ⚠
Domain found in IF2B/IF5, putative
— Both
LAMA_000357500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000017300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000328100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000129500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000014300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000575700 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000091100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000292500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000157800 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000014900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000797600 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— Both
LAMA_000533800 ⚠
Calpain family cysteine protease/Calpain larg
— Both
LAMA_000533600 ⚠
Calpain family cysteine protease/Calpain larg
— Both
LAMA_000127600 ⚠
hypothetical protein
— Both
LAMA_000554500 ⚠
hypothetical protein, conserved
— Both
LAMA_000113700 ⚠
hypothetical protein, conserved
— Both
LAMA_000427400 ⚠
hypothetical protein, conserved
— Both
LAMA_000750800 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000591900 ⚠
Domain of unknown function (DUF382)/PSP, puta
— Both
LAMA_000097100 ⚠
hypothetical protein, conserved
— Both
LAMA_000319300 ⚠
Tetratricopeptide repeat/NMDA receptor-regula
— Both
LAMA_000230300 ⚠
hypothetical protein
— OG6
LAMA_000014400 ⚠
hypothetical protein
— Both
LAMA_000271600 ⚠
Eukaryotic translation initiation factor eIF2
— Both
LAMA_000103800 ⚠
Ribosomal protein L13e, putative
— Both
LAMA_000024100 ⚠
Ribosomal protein L13e, putative
— Both
LAMA_000688600 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000579300 ⚠
Biotin-requiring enzyme/2-oxoacid dehydrogena
— Both
LAMA_000190600 ⚠
hypothetical protein, conserved
— Both
LAMA_000401200 ⚠
Biotin-requiring enzyme, putative
— Both
LAMA_000623600 ⚠
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.