LAMA_000113700

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146709 OG7: OG7_0043725 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000136800
hypothetical protein, conserved
— Both
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000463700 ⚠
Rad17 P-loop domain/ATPase family associated
— OG7
LAMA_000172800 ⚠
Proteasome subunit A N-terminal signature/Pro
— Both
LAMA_000203800 ⚠
RNA polymerases N / 8 kDa subunit, putative
— Both
LAMA_000491200 ⚠
RNA polymerases N / 8 kDa subunit, putative
— Both
LAMA_000067600 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— Both
LAMA_000555700
Proteasome subunit, putative
— Both
LAMA_000745100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000160100
hypothetical protein, conserved
— Both
LAMA_000029200
hypothetical protein, conserved
— Both
LAMA_000385500
hypothetical protein, conserved
— Both
LAMA_000789300
Helicase conserved C-terminal domain containi
— OG6
LAMA_000652000
Biotin carboxylase, N-terminal domain/Carbamo
— Both
LAMA_000615900
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000388300 ⚠
hypothetical protein, conserved
— Both
LAMA_000409200
hypothetical protein, conserved
— Both
LAMA_000690100 ⚠
3' exoribonuclease family, domain 1/3' exorib
— Both
LAMA_000433200 ⚠
3' exoribonuclease family, domain 1, putative
— Both
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000755700 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAMA_000157800 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000292500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000091100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000575700 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000014300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000129500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000323000 ⚠
Proteasome subunit, putative
— OG7
LAMA_000328100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000156300
hypothetical protein, conserved
— Both
LAMA_000322400 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000416900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000213000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000530500 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000541800 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000209500 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000377000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000805000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000024700
hypothetical protein, conserved
— Both
LAMA_000408000 ⚠
TCP-1/cpn60 chaperonin family, putative
— Both
LAMA_000221500
'Cold-shock' DNA-binding domain containing pr
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.