LAMA_000789300

Helicase conserved C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146576 OG7: OG7_0000698 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000106300
Leucine-rich repeat/Leucine rich repeat, puta
— OG6
LAMA_000081500
Ctf8, putative
— OG6
LAMA_000473200
Cyclin/Cyclin, N-terminal domain containing p
— OG6
LAMA_000232200
hypothetical protein, conserved
— OG6
LAMA_000232500
hypothetical protein, conserved
— OG6
LAMA_000721900
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG6
LAMA_000600400
Flavoprotein, putative
— OG6
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— OG6
LAMA_000724100
Concanavalin A-like lectin/glucanases superfa
— OG6
LAMA_000740600
hypothetical protein, conserved
— OG6
LAMA_000495000
hypothetical protein, conserved
— OG6
LAMA_000115400
Hsp70 protein/Tetratricopeptide repeat, putat
— OG6
LAMA_000013500
M17 aminopeptidase N-terminal domain 2, putat
— OG6
LAMA_000621500
hypothetical protein, conserved
— OG6
LAMA_000593700
hypothetical protein, conserved
— OG6
LAMA_000616200
tRNA (Guanine-1)-methyltransferase, putative
— OG6
LAMA_000141900
AAA domain (dynein-related subfamily)/AAA dom
— OG6
LAMA_000271800
Methyltransferase domain containing protein,
— OG6
LAMA_000090400
HECT-domain (ubiquitin-transferase), putative
— OG6
LAMA_000064000
Ferrous iron transport protein B/50S ribosome
— OG6
LAMA_000551000 ⚠
Phosducin/Thioredoxin, putative
— OG6
LAMA_000684900 ⚠
Phosducin/Thioredoxin, putative
— OG6
LAMA_000095200
HEAT repeat, putative
— OG6
LAMA_000269000
hypothetical protein, conserved
— OG6
LAMA_000147600
Acyl CoA binding protein, putative
— OG6
LAMA_000273000
ZPR1 zinc-finger domain containing protein, p
— OG6
LAMA_000636400
hypothetical protein, conserved
— OG6
LAMA_000008100
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000509400
Regulator of chromosome condensation (RCC1) r
— OG6
LAMA_000115300
hypothetical protein, conserved
— OG6
LAMA_000605600
Calpain family cysteine protease, putative
— OG6
LAMA_000235700
ThiF family, putative
— OG6
LAMA_000225400 ⚠
TATA box binding protein associated factor (T
— OG6
LAMA_000780200 ⚠
TATA box binding protein associated factor (T
— OG6
LAMA_000369100
hypothetical protein, conserved
— OG6
LAMA_000545300
hypothetical protein, conserved
— OG6
LAMA_000010100
FYVE zinc finger containing protein, putative
— OG6
LAMA_000347500
hypothetical protein, conserved
— OG6
LAMA_000362600
tRNA synthetases class I (I, L, M and V)/Anti
— OG6
LAMA_000812000
SET domain containing protein, putative
— OG6
LAMA_000362300
Adenylate cyclase associated (CAP) N terminal
— OG6
LAMA_000448800 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG6
LAMA_000664300 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG6
LAMA_000128200
tRNA synthetases class I (W and Y), putative
— OG6
LAMA_000196400
Acetyltransferase (GNAT) family/Acetyltransfe
— OG6
LAMA_000524800
hypothetical protein, conserved
— OG6
LAMA_000513200
RNA pseudouridylate synthase, putative
— OG6
LAMA_000031500
Aspartyl protease/gag-polyprotein putative as
— OG6
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG6
LAMA_000507100
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.