LAMA_000141900

AAA domain (dynein-related subfamily)/AAA domain (Cdc48 subfamily)/ATPase family associated with various cellular activities (AAA)/C-terminal, D2-small domain, of ClpB protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_137689 OG7: OG7_0004131 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000420700
SEP domain containing protein, putative
— OG7
LAMA_000034900
hypothetical protein, conserved
— OG7
LAMA_000547200 ⚠
Paraflagellar rod protein/Variant SH3 domain/
— OG7
LAMA_000122000 ⚠
Radial spokehead-like protein, putative
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000242200 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000306800 ⚠
mRNA capping enzyme, putative
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000475400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000502800 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000665000 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000368600 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000571200 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000576500 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000380400 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000321000 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000343500
NUDIX domain containing protein, putative
— OG7
LAMA_000574300 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000101700 ⚠
FYVE zinc finger/3'5'-cyclic nucleotide phosp
— OG7
LAMA_000595100 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAMA_000297500
Putative TPR-like repeat/Anaphase-promoting c
— OG7
LAMA_000284200 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000114700 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— OG7
LAMA_000702600
WD domain, G-beta repeat, putative
— OG7
LAMA_000495100
hypothetical protein, conserved
— OG7
LAMA_000771600
Enoyl-CoA hydratase/isomerase, putative
— OG7
LAMA_000126200 ⚠
non-haem dioxygenase in morphine synthesis N-
— OG7
LAMA_000517300 ⚠
Peptidase family M3, putative
— OG7
LAMA_000104000 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000791800
hypothetical protein, conserved
— OG7
LAMA_000268200 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000333100
hypothetical protein, conserved
— OG7
LAMA_000116000
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.