LAMA_000116000

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_200029 OG7: OG7_0051972 117 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 117 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000297500
Putative TPR-like repeat/Anaphase-promoting c
— OG7
LAMA_000496800
Not1 N-terminal domain, CCR4-Not complex comp
— Both
LAMA_000117800
Kinesin motor domain/Microtubule binding, put
— OG6
LAMA_000474000
hypothetical protein, conserved
— Both
LAMA_000189000 ⚠
WW domain containing protein, putative
— Both
LAMA_000219200
hypothetical protein, conserved
— Both
LAMA_000396400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
LAMA_000068400 ⚠
hypothetical protein, conserved
— Both
LAMA_000085800
hypothetical protein, conserved
— Both
LAMA_000520700
hypothetical protein, conserved
— Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— Both
LAMA_000183700 ⚠
Initiation factor 2 subunit family, putative
— Both
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— Both
LAMA_000532300 ⚠
hypothetical protein
— Both
LAMA_000432500
DEAD/DEAH box helicase/AAA domain/Helicase co
— OG6
LAMA_000422900
AAA domain (dynein-related subfamily)/AAA dom
— OG6
LAMA_000153100
ATPase family associated with various cellula
— Both
LAMA_000257100
WD domain, G-beta repeat, putative
— OG7
LAMA_000541200 ⚠
Initiation factor 2 subunit family, putative
— OG7
LAMA_000166000 ⚠
Initiation factor 2 subunit family, putative
— OG7
LAMA_000073300 ⚠
MORN repeat, putative
— OG7
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000034900
hypothetical protein, conserved
— OG7
LAMA_000277500 ⚠
Ubiquitin-like domain/CAP-Gly domain containi
— OG7
LAMA_000017400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000547500
hypothetical protein, conserved
— OG7
LAMA_000207800 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000582800 ⚠
Gamma tubulin complex component N-terminal/Ga
— OG7
LAMA_000414200 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000336500 ⚠
3' exoribonuclease family, domain 1/3' exorib
— OG7
LAMA_000270200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000270100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000333100
hypothetical protein, conserved
— OG7
LAMA_000579000 ⚠
WW domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.