LAMA_000801800

AAA ATPase domain/RecF/RecN/SMC N terminal domain/P-loop containing region of AAA domain/AAA domain, putative AbiEii toxin, Type IV TA system/SMC proteins Flexible Hinge Domain, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101499 OG7: OG7_0001761 204 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 204 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000576100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000164400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— +2 more OG7
LAMA_000512400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000415700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000647800 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000569900 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000440400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000464300 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LAMA_000295900 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000657400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000717200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000593000 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000706700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000766500 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG7
LAMA_000634500 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LAMA_000724100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAMA_000520700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000667900 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000586100 ⚠
MATH domain containing protein, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000757500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000329200 ⚠
Gamma tubulin complex component N-terminal, p
— OG7
LAMA_000315800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000417400 ⚠
Histone deacetylase domain containing protein
— OG7
LAMA_000162200 ⚠
Chromatin assembly factor 1 subunit A, putati
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000484600 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000743500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000652000 ⚠
Biotin carboxylase, N-terminal domain/Carbamo
— OG7
LAMA_000071000 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— OG7
LAMA_000496800 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LAMA_000588300 ⚠
Ubiquitin carboxyl-terminal hydrolase/Exonucl
— OG7
LAMA_000653500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000764500 ⚠
GRIP domain containing protein, putative
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— +2 more OG7
LAMA_000622600 ⚠
CPSF A subunit region containing protein, put
— OG7
LAMA_000599000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000591000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000481000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000697700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000299100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000668900 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.