LAMA_000315800

WD domain, G-beta repeat, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_104180 OG7: OG7_0007173 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000586100
MATH domain containing protein, putative
— Both
LAMA_000607500
GYF domain 2/DnaJ domain containing protein,
— Both
LAMA_000284100
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000085800
hypothetical protein, conserved
— Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— Both
LAMA_000592700
Phosphatidylinositol-specific phospholipase C
— Both
LAMA_000593000
Tetratricopeptide repeat, putative
— Both
LAMA_000153100
ATPase family associated with various cellula
— Both
LAMA_000073300 ⚠
MORN repeat, putative
— OG7
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000657400
hypothetical protein, conserved
— Both
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000207800 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000434400
hypothetical protein, conserved
— Both
LAMA_000554300
Prp19/Pso4-like/WD domain, G-beta repeat, put
— Both
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— Both
LAMA_000262000
hypothetical protein, conserved
— Both
LAMA_000138900
Anaphase-promoting complex subunit 4 WD40 dom
— Both
LAMA_000653500
hypothetical protein, conserved
— Both
LAMA_000370200 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LAMA_000071400
Paraflagellar rod protein, putative
— Both
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— Both
LAMA_000299100
WD domain, G-beta repeat, putative
— Both
LAMA_000656800
hypothetical protein, conserved
— Both
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LAMA_000415700
hypothetical protein, conserved
— Both
LAMA_000092600
Dynein heavy chain, N-terminal region 2, puta
— OG6
LAMA_000116000
hypothetical protein, conserved
— Both
LAMA_000055500
Tetratricopeptide repeat, putative
— Both
LAMA_000667900
Mono-functional DNA-alkylating methyl methane
— Both
LAMA_000050100 ⚠
MORN repeat, putative
— Both
LAMA_000063900
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— Both
LAMA_000433700
CAF1 family ribonuclease, putative
— Both
LAMA_000057000
Axonemal dynein light chain, putative
— Both
LAMA_000296300 ⚠
hypothetical protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.