LAMA_000433700

CAF1 family ribonuclease, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101138 OG7: OG7_0005422 143 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 143 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000403900
CCR4-NOT transcription complex subunit 1 TTP
— Both
LAMA_000496800
Not1 N-terminal domain, CCR4-Not complex comp
— Both
LAMA_000187300
NOT2 / NOT3 / NOT5 family, putative
— Both
LAMA_000767300
Cell differentiation family, Rcd1-like, putat
— Both
LAMA_000434400
hypothetical protein, conserved
— Both
LAMA_000057000
Axonemal dynein light chain, putative
— Both
LAMA_000607200
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000255000 ⚠
RNA polymerase Rpb1, domain 2/RNA polymerase
— Both
LAMA_000296300 ⚠
hypothetical protein
— OG6
LAMA_000024000 ⚠
Kinesin motor domain/Microtubule binding, put
— OG6
LAMA_000296100 ⚠
hypothetical protein
— OG6
LAMA_000296400 ⚠
hypothetical protein, conserved
— OG6
LAMA_000433300
hypothetical protein, conserved
— Both
LAMA_000215700
WD domain, G-beta repeat, putative
— Both
LAMA_000085800
hypothetical protein, conserved
— Both
LAMA_000245300 ⚠
Tubulin-tyrosine ligase family, putative
— Both
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— Both
LAMA_000153100
ATPase family associated with various cellula
— Both
LAMA_000607300
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000073300 ⚠
MORN repeat, putative
— OG7
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000126100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000684500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000174400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000619300
hypothetical protein, conserved
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000267900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000477400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000723300 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000462900 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000207800 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.