LAMA_000207800

SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_158186 OG7: OG7_0009410 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000290700 ⚠
Fibrillarin/tRNA methyltransferase complex GC
— OG7
LAMA_000586100 ⚠
MATH domain containing protein, putative
— OG7
LAMA_000592700 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000697700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000077700 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000184900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000701800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000407500 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000299100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000656800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000085800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000496800 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LAMA_000403900 ⚠
CCR4-NOT transcription complex subunit 1 TTP
— OG7
LAMA_000667900 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000055500 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000217900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000380900 ⚠
AAA domain (dynein-related subfamily)/Midasin
— OG7
LAMA_000653500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000116000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000462200 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000401000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000474000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000434400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000236800 ⚠
Cyclic nucleotide-binding domain/PAS fold/Pro
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000065900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000189900 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000657400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.