LAMA_000701800

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_149201 OG7: OG7_0044538 31 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 31 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000648100 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— Both
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000207800 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000005300 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000011500 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— OG7
LAMA_000311800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000809900 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
LAMA_000582700 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— OG7
LAMA_000745800 ⚠
Endonuclease/Exonuclease/phosphatase family,
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000696100
snoRNA binding domain, fibrillarin, putative
— Both
LAMA_000370200 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— Both
LAMA_000648200 ⚠
HI0933-like protein/Pyridine nucleotide-disul
— Both
LAMA_000212900
hypothetical protein, conserved
— Both
LAMA_000285600 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— Both
LAMA_000409100
WD domain, G-beta repeat, putative
— OG6
LAMA_000214100
mRNA capping enzyme, beta chain, putative
— Both
LAMA_000683600
CS domain containing protein, putative
— Both
LAMA_000287700
2Fe-2S iron-sulfur cluster binding domain/NAD
— Both
LAMA_000358700
Glycosyl hydrolase family 65, N-terminal doma
— Both
LAMA_000564400 ⚠
hypothetical protein, conserved
— Both
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— Both
LAMA_000077700 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— Both
LAMA_000656200
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.