LAMA_000285600

PIH1 N-terminal domain/PIH1 CS-like domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_105060 OG7: OG7_0006226 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000683600 ⚠
CS domain containing protein, putative
— Both
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000582700 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— OG7
LAMA_000347000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000134500 ⚠
Domain found in IF2B/IF5, putative
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000507300 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000444200 ⚠
hypothetical protein, conserved
— Both
LAMA_000212900 ⚠
hypothetical protein, conserved
— Both
LAMA_000409100
WD domain, G-beta repeat, putative
— OG6
LAMA_000214100 ⚠
mRNA capping enzyme, beta chain, putative
— Both
LAMA_000287700 ⚠
2Fe-2S iron-sulfur cluster binding domain/NAD
— Both
LAMA_000358700 ⚠
Glycosyl hydrolase family 65, N-terminal doma
— Both
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000127800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000456400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000693600 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000221400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— OG7
LAMA_000647800 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000255000 ⚠
RNA polymerase Rpb1, domain 2/RNA polymerase
— OG7
LAMA_000311800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000187400 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAMA_000711100 ⚠
Glutathione S-transferase, N-terminal domain/
— OG7
LAMA_000094900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000005300 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000054900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000011500 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— OG7
LAMA_000232600 ⚠
hypothetical protein, conserved
— Both
LAMA_000430300 ⚠
MORN repeat, putative
— Both
LAMA_000665600 ⚠
hypothetical protein, conserved
— Both
LAMA_000737500 ⚠
hypothetical protein, conserved
— Both
LAMA_000722600 ⚠
hypothetical protein, conserved
— Both
LAMA_000409400 ⚠
hypothetical protein, conserved
— Both
LAMA_000464300 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
LAMA_000773400 ⚠
hypothetical protein, conserved
— Both
LAMA_000616100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— Both
LAMA_000632200 ⚠
hypothetical protein, conserved
— Both
LAMA_000711600 ⚠
hypothetical protein, conserved
— Both
LAMA_000615900 ⚠
Eukaryotic translation initiation factor 3 su
— Both
LAMA_000494200 ⚠
hypothetical protein, conserved
— Both
LAMA_000581500 ⚠
Adaptin N terminal region/Coatomer gamma subu
— Both
LAMA_000525000 ⚠
Zn-finger in Ran binding protein and others/S
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.