LAMA_000255000

RNA polymerase Rpb1, domain 2/RNA polymerase Rpb1, domain 3/RNA polymerase Rpb1, domain 4/RNA polymerase Rpb1, domain 5, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101773 OG7: OG7_0001854 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— Both
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— +1 more OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— +1 more OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000484600 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— +3 more Both
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000295900 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— +1 more Both
LAMA_000652000 ⚠
Biotin carboxylase, N-terminal domain/Carbamo
— Both
LAMA_000576100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000232600 ⚠
hypothetical protein, conserved
— Both
LAMA_000245300 ⚠
Tubulin-tyrosine ligase family, putative
— Both
LAMA_000555800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000293700 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000111100 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— OG7
LAMA_000406800 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000126100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000684500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000174400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000737700 ⚠
RNA polymerase Rpb6, putative
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000684700 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000149100 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000336900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000094900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000054900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000285600 ⚠
PIH1 N-terminal domain/PIH1 CS-like domain co
— OG7
LAMA_000507300 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.