LAMA_000378400

RNA polymerase beta subunit/RNA polymerase Rpb2, domain 2/RNA polymerase Rpb2, domain 3/RNA polymerase Rpb2, domain 4/RNA polymerase Rpb2, domain 5/RNA polymerase Rpb2, domain 6/RNA polymerase Rpb2, domain 7, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100190 OG7: OG7_0001821 174 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 174 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000295900 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— Both
LAMA_000575500 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— +1 more Both
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— Both
LAMA_000452400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000051500 ⚠
KH domain containing protein, putative
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— +4 more Both
LAMA_000647800 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— +4 more Both
LAMA_000648200 ⚠
HI0933-like protein/Pyridine nucleotide-disul
— Both
LAMA_000544100 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— Both
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000648100 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000255000 ⚠
RNA polymerase Rpb1, domain 2/RNA polymerase
— +1 more OG7
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000267900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000019500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000111100 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— OG7
LAMA_000210000 ⚠
KH domain containing protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000491900 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LAMA_000031800 ⚠
Hsp70 protein, putative
— OG7
LAMA_000433700 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000174400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000684500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000126100 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000245300 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000336500 ⚠
3' exoribonuclease family, domain 1/3' exorib
— OG7
LAMA_000093300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000433200 ⚠
3' exoribonuclease family, domain 1, putative
— OG7
LAMA_000690100 ⚠
3' exoribonuclease family, domain 1/3' exorib
— OG7
LAMA_000298500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000232600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000356300 ⚠
3' exoribonuclease family, domain 1, putative
— OG7
LAMA_000348600 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000012700 ⚠
3' exoribonuclease family, domain 1, putative
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000293700 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000433300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000173000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000164400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.