LAMA_000051500

KH domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102463 OG7: OG7_0007513 169 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 169 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000012700 ⚠
3' exoribonuclease family, domain 1, putative
— Both
LAMA_000452400
hypothetical protein, conserved
— Both
LAMA_000336500 ⚠
3' exoribonuclease family, domain 1/3' exorib
— Both
LAMA_000433200 ⚠
3' exoribonuclease family, domain 1, putative
— +2 more Both
LAMA_000356300 ⚠
3' exoribonuclease family, domain 1, putative
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000391100
hypothetical protein, conserved
— Both
LAMA_000484600 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— Both
LAMA_000210000
KH domain containing protein, putative
— Both
LAMA_000690100 ⚠
3' exoribonuclease family, domain 1/3' exorib
— +2 more Both
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000019500 ⚠
hypothetical protein, conserved
— Both
LAMA_000019400 ⚠
hypothetical protein, conserved
— Both
LAMA_000491900 ⚠
Conserved hypothetical ATP binding protein, p
— Both
LAMA_000043900
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000021900 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000507200 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000684700 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000555800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000347000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000619900 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000149100 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000293700 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000054900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.