LAMA_000619900

Temperature dependent protein affecting M2 dsRNA replication, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_109072 OG7: OG7_0013037 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000167600 ⚠
Ataxin 2 SM domain/LsmAD domain containing pr
— Both
LAMA_000054900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000094900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000507300 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000347000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000257600 ⚠
MIF4G domain containing protein, putative
— OG7
LAMA_000367400 ⚠
MIF4G domain containing protein, putative
— OG7
LAMA_000157600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000378300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000171800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000776700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000091500 ⚠
RAVE protein 1 C terminal, putative
— OG7
LAMA_000287000 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000597400 ⚠
Armadillo/beta-catenin-like repeat/Atypical A
— OG7
LAMA_000306000 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000707100 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000584600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000415800 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000187600 ⚠
Pumilio-family RNA binding repeat, putative
— OG7
LAMA_000358700 ⚠
Glycosyl hydrolase family 65, N-terminal doma
— OG7
LAMA_000020900 ⚠
WD domain, G-beta repeat/WD40-like Beta Prope
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000293700 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000634500 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LAMA_000348600 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000508100 ⚠
Myosin-like coiled-coil protein, putative
— OG7
LAMA_000587200 ⚠
Leucine Rich repeat/Leucine Rich Repeat, puta
— OG7
LAMA_000433300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000555800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000391100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000621200 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000777400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000227000 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAMA_000529900 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LAMA_000226900 ⚠
hypothetical protein
— OG7
LAMA_000051500 ⚠
KH domain containing protein, putative
— OG7
LAMA_000755700 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAMA_000566700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000286300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000286100 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.