LAMA_000391100

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146086 OG7: OG7_0043575 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000051500
KH domain containing protein, putative
— Both
LAMA_000347000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000019400 ⚠
hypothetical protein, conserved
— Both
LAMA_000336500 ⚠
3' exoribonuclease family, domain 1/3' exorib
— Both
LAMA_000091500
RAVE protein 1 C terminal, putative
— Both
LAMA_000094900 ⚠
hypothetical protein, conserved
— Both
LAMA_000043900
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000555800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000619900 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000293700 ⚠
Transcription factor S-II (TFIIS), putative
— OG7
LAMA_000021200 ⚠
Hsp70 protein, putative
— Both
LAMA_000507300 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000054900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000031800 ⚠
Hsp70 protein, putative
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000012700 ⚠
3' exoribonuclease family, domain 1, putative
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000507200 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000433200 ⚠
3' exoribonuclease family, domain 1, putative
— Both
LAMA_000232000
Kelch motif/Galactose oxidase, central domain
— Both
LAMA_000358700
Glycosyl hydrolase family 65, N-terminal doma
— Both
LAMA_000433300
hypothetical protein, conserved
— Both
LAMA_000508100
Myosin-like coiled-coil protein, putative
— Both
LAMA_000348600 ⚠
Transcription factor S-II (TFIIS), putative
— Both
LAMA_000634500
Protein of unknown function (DUF3638)/Protein
— Both
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— Both
LAMA_000452400
hypothetical protein, conserved
— Both
LAMA_000491900 ⚠
Conserved hypothetical ATP binding protein, p
— Both
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
LAMA_000021900 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000737100 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000356300 ⚠
3' exoribonuclease family, domain 1, putative
— Both
LAMA_000320600 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAMA_000210000
KH domain containing protein, putative
— Both
LAMA_000484600 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— Both
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
LAMA_000690100 ⚠
3' exoribonuclease family, domain 1/3' exorib
— Both
LAMA_000019500 ⚠
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.