LAMA_000348600

Transcription factor S-II (TFIIS), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_151929 OG7: OG7_0002891 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000406800 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— OG7
LAMA_000575500 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000491200 ⚠
RNA polymerases N / 8 kDa subunit, putative
— OG7
LAMA_000124700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000111100 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— OG7
LAMA_000737700 ⚠
RNA polymerase Rpb6, putative
— OG7
LAMA_000647800 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000563100 ⚠
RNA polymerase Rpb8, putative
— OG7
LAMA_000544100 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000203800 ⚠
RNA polymerases N / 8 kDa subunit, putative
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000347000 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000507300 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000054900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAMA_000295600 ⚠
Core histone H2A/H2B/H3/H4/Histone-like trans
— OG7
LAMA_000667100 ⚠
SHS2 domain found in N terminus of Rpb7p/Rpc2
— OG7
LAMA_000151600 ⚠
SHS2 domain found in N terminus of Rpb7p/Rpc2
— OG7
LAMA_000382800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000619900 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000094900 ⚠
hypothetical protein, conserved
— Both
LAMA_000232000 ⚠
Kelch motif/Galactose oxidase, central domain
— Both
LAMA_000281100 ⚠
RNA polymerase Rpb5, N-terminal domain/RNA po
— Both
LAMA_000058800 ⚠
hypothetical protein, conserved
— Both
LAMA_000508100 ⚠
Myosin-like coiled-coil protein, putative
— Both
LAMA_000391100 ⚠
hypothetical protein, conserved
— Both
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— Both
LAMA_000091500 ⚠
RAVE protein 1 C terminal, putative
— Both
LAMA_000281000 ⚠
RNA polymerase Rpb5, N-terminal domain/RNA po
— Both
LAMA_000358700 ⚠
Glycosyl hydrolase family 65, N-terminal doma
— Both
LAMA_000295900 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— Both
LAMA_000051500 ⚠
KH domain containing protein, putative
— Both
LAMA_000255000 ⚠
RNA polymerase Rpb1, domain 2/RNA polymerase
— Both
LAMA_000484600 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— Both
LAMA_000260500 ⚠
Core histone H2A/H2B/H3/H4/C-terminus of hist
— Both
LAMA_000433300 ⚠
hypothetical protein, conserved
— Both
LAMA_000043900 ⚠
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000232600 ⚠
hypothetical protein, conserved
— Both
LAMA_000634500 ⚠
Protein of unknown function (DUF3638)/Protein
— Both
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000479500 ⚠
RNA polymerase Rpb6, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.