LAMA_000514200

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_478916 OG7: OG7_0001169 236 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 236 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000178900 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000536900 ⚠
Right handed beta helix region/Periplasmic co
— OG7
LAMA_000439600 ⚠
Glycogen recognition site of AMP-activated pr
— OG7
LAMA_000569900 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000717200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000706700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000634500 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LAMA_000626300 ⚠
hypothetical protein
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000763900 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000757500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000764500 ⚠
GRIP domain containing protein, putative
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000599000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000588300 ⚠
Ubiquitin carboxyl-terminal hydrolase/Exonucl
— OG7
LAMA_000751700 ⚠
RNA-binding signal recognition particle 68, p
— OG7
LAMA_000329200 ⚠
Gamma tubulin complex component N-terminal, p
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000626600 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAMA_000652000 ⚠
Biotin carboxylase, N-terminal domain/Carbamo
— OG7
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
LAMA_000516300 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000334800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000661400 ⚠
Pan3 Pseudokinase domain containing protein,
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000071100 ⚠
CPSF A subunit region containing protein, put
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000512400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000368700 ⚠
Sucrase/ferredoxin-like, putative
— OG7
LAMA_000012800 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000718000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000619700 ⚠
Dynein heavy chain region D6 P-loop domain co
— OG7
LAMA_000331000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000723700 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.