LAMA_000128800

AAA ATPase domain/RecF/RecN/SMC N terminal domain/AAA domain/SMC proteins Flexible Hinge Domain, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101525 OG7: OG7_0001761 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000351200 ⚠
Gamma tubulin complex component N-terminal/Ga
— OG7
LAMA_000653500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— +2 more OG7
LAMA_000668900 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— OG7
LAMA_000591000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000697700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000496800 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000743500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000315800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000336900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000433700 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— +2 more OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000380900 ⚠
AAA domain (dynein-related subfamily)/Midasin
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000554300 ⚠
Prp19/Pso4-like/WD domain, G-beta repeat, put
— OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000710500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000656800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000592700 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000040100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000748400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000017400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000048200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000043100 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000184900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000077700 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000270300 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— +2 more OG7
LAMA_000462200 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000582800 ⚠
Gamma tubulin complex component N-terminal/Ga
— OG7
LAMA_000434400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000403900 ⚠
CCR4-NOT transcription complex subunit 1 TTP
— OG7
LAMA_000445700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000414200 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000607500 ⚠
GYF domain 2/DnaJ domain containing protein,
— OG7
LAMA_000576100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.