LAMA_000173000

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147362 OG7: OG7_0037845 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000687200
hypothetical protein, conserved
— Both
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000278600
Flagellar-associated PapD-like, putative
— Both
LAMA_000215700
WD domain, G-beta repeat, putative
— Both
LAMA_000093300
hypothetical protein, conserved
— Both
LAMA_000789300
Helicase conserved C-terminal domain containi
— OG6
LAMA_000059000
DnaJ domain/DnaJ C terminal domain containing
— Both
LAMA_000786200
hypothetical protein, conserved
— Both
LAMA_000547500
hypothetical protein, conserved
— Both
LAMA_000052900 ⚠
Alcohol dehydrogenase GroES-like domain conta
— Both
LAMA_000072300
Respiratory-chain NADH dehydrogenase 51 Kd su
— Both
LAMA_000592000
AMP-binding enzyme, putative
— Both
LAMA_000067100 ⚠
hypothetical protein, conserved
— Both
LAMA_000121600
hypothetical protein, conserved
— Both
LAMA_000575200
GRIM-19 protein, putative
— Both
LAMA_000585900
hypothetical protein, conserved
— Both
LAMA_000164600
hypothetical protein, conserved
— Both
LAMA_000524100
hypothetical protein, conserved
— Both
LAMA_000531400
Phosphopantetheine attachment site, putative
— Both
LAMA_000260400
Thioredoxin-like [2Fe-2S] ferredoxin, putativ
— Both
LAMA_000067900
hypothetical protein, conserved
— Both
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000684700 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000149100 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— OG7
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000336900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000209500 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000267900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000276500 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000276600 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000174400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000805000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000377000 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LAMA_000322400 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000323000 ⚠
Proteasome subunit, putative
— OG7
LAMA_000416900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.