LAMA_000323000

Proteasome subunit, putative

Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100897 OG7: OG7_0001933 53 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 53 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAMA_000804800 ⚠ Proteasome subunit, putative	—	OG6 LdBPK_353880.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 OG7 LdBPK_353880.1 ↔ LdBPK_361730.1 +2 more	Both
LAMA_000416000 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 Tb927.10.290 ↔ Tb927.10.6080 OG6 LdBPK_212070.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
LAMA_000076200 ⚠ Proteasome subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.7.4790 OG6 LdBPK_060140.1 ↔ LdBPK_361730.1 OG7 TCSYLVIO_002482 ↔ TCSYLVIO_006999 OG7 LdBPK_060140.1 ↔ LdBPK_120030.1 +4 more	Both
LAMA_000555700 ⚠ Proteasome subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
LAMA_000814900 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 Tb927.10.6080 ↔ Tb927.9.9670 OG6 LdBPK_354910.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
LAMA_000213000 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 Tb927.10.6080 ↔ Tb927.7.4420 OG6 LdBPK_140310.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
LAMA_000530500 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 Tb927.10.6080 ↔ Tb927.3.780 OG6 LdBPK_270190.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
LAMA_000322400 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 LdBPK_361670.1 ↔ LdBPK_361730.1 OG6 Tb11.v5.0196 ↔ Tb927.10.6080 OG6 Tb927.10.6030 ↔ Tb927.10.6080 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 +44 more	Both
LAMA_000183900 ⚠ Proteasome subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.6.1260 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 +3 more	Both
LAMA_000416900 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 Tb927.10.230 ↔ Tb927.10.6080 OG6 LdBPK_212200.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
LAMA_000308800 ⚠ Proteasome subunit, putative	—	OG6 LdBPK_360340.1 ↔ LdBPK_361730.1 OG6 Tb927.10.4710 ↔ Tb927.10.6080 OG7 LdBPK_120030.1 ↔ LdBPK_360340.1 OG7 LdBPK_353880.1 ↔ LdBPK_360340.1 +4 more	Both
LAMA_000172800 ⚠ Proteasome subunit A N-terminal signature/Pro	—	OG6 LdBPK_110240.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.11.7020 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
LAMA_000408000 ⚠ TCP-1/cpn60 chaperonin family, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LAMA_000664300 ⚠ TCP-1/cpn60 chaperonin family, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LAMA_000688200 ⚠ TCP-1/cpn60 chaperonin family, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LAMA_000541800 ⚠ TCP-1/cpn60 chaperonin family, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LAMA_000336300 ⚠ DEAD/DEAH box helicase/Type III restriction e	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
LAMA_000652000 ⚠ Biotin carboxylase, N-terminal domain/Carbamo	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_006999	OG7
LAMA_000047100 ⚠ DEAD/DEAH box helicase/Type III restriction e	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
LAMA_000732800 ⚠ Domain found in IF2B/IF5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
LAMA_000041700 ⚠ Acetyltransferase (GNAT) family/Acetyltransfe	—	OG7 TCSYLVIO_004519 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_006999	OG7
LAMA_000113700 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_006999	OG7
LAMA_000006500 ⚠ PMC2NT (NUC016) domain/3'-5' exonuclease/HRDC	—	OG7 TCSYLVIO_003804 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_006999	OG7
LAMA_000715600 ⚠ N-terminal domain of ribose phosphate pyropho	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
LAMA_000360300 ⚠ N-terminal domain of ribose phosphate pyropho	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
LAMA_000221500 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
LAMA_000295900 ⚠ RNA polymerase Rpb3/Rpb11 dimerisation domain	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
LAMA_000138300 ⚠ N-terminal domain of ribose phosphate pyropho	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
LAMA_000173000 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001704 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_006999	OG7
LAMA_000599000 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003184 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003184 ↔ TCSYLVIO_004939	Both
LAMA_000133900 ⚠ N-terminal domain of ribose phosphate pyropho	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
LAMA_000684900 ⚠ Phosducin/Thioredoxin, putative	—	OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	OG7
LAMA_000551000 ⚠ Phosducin/Thioredoxin, putative	—	OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	OG7
LAMA_000468200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_009798 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_009798	Both
LAMA_000030700 ⚠ pre-mRNA processing factor 3 (PRP3)/Protein o	—	OG6 TCSYLVIO_003433 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003433 ↔ TCSYLVIO_004939	Both
LAMA_000741000 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003934 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003934 ↔ TCSYLVIO_004939	Both
LAMA_000683300 ⚠ 26S proteasome subunit RPN7/PCI domain contai	—	OG6 Tb927.10.6080 ↔ Tb927.11.16030 OG7 Tb927.10.6080 ↔ Tb927.11.16030	Both
LAMA_000767000 ⚠ Proteasome subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.4.430 OG7 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.10.6080 ↔ Tb927.4.430	Both
LAMA_000127300 ⚠ RNA polymerase Rpb3/Rpb11 dimerisation domain	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010718 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	Both
LAMA_000485800 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_007412 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_007412	Both
LAMA_000140900 ⚠ BILBO1 N-terminal domain/EF-hand domain pair,	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_006469 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	Both
LAMA_000154200 ⚠ Paraflagellar rod protein, putative	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_006797 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006797	Both
LAMA_000210000 ⚠ KH domain containing protein, putative	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010369 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010369	Both
LAMA_000209500 ⚠ TCP-1/cpn60 chaperonin family, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LAMA_000129600 ⚠ Adaptin N terminal region/non-SMC mitotic con	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010530 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010530	Both
LAMA_000433200 ⚠ 3' exoribonuclease family, domain 1, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LAMA_000690100 ⚠ 3' exoribonuclease family, domain 1/3' exorib	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LAMA_000513000 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002300 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_002300 ↔ TCSYLVIO_004939	Both
LAMA_000751700 ⚠ RNA-binding signal recognition particle 68, p	—	OG6 TCSYLVIO_003828 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003828 ↔ TCSYLVIO_004939	Both
LAMA_000403400 ⚠ PCI domain/26S proteasome regulatory subunit	—	OG7 Tb927.10.1550 ↔ Tb927.6.1260	OG7

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