LAMA_000030700

pre-mRNA processing factor 3 (PRP3)/Protein of unknown function (DUF1115), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_157627 OG7: OG7_0043643 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000011500 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— Both
LAMA_000443200
Mitosis protein DIM1, putative
— Both
LAMA_000260700
LSM domain containing protein, putative
— Both
LAMA_000811100 ⚠
LSM domain containing protein, putative
— Both
LAMA_000728200
LSM domain containing protein, putative
— Both
LAMA_000676700 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000257900
snoRNA binding domain, fibrillarin, putative
— Both
LAMA_000679800
hypothetical protein, conserved
— Both
LAMA_000806000
PRO8NT (NUC069), PrP8 N-terminal domain/PROCN
— Both
LAMA_000502800 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000598300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000582700 ⚠
WD domain, G-beta repeat/Eukaryotic translati
— OG7
LAMA_000311800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000548400
LSM domain containing protein, putative
— Both
LAMA_000005300 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000414200 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— OG7
LAMA_000661300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000311200 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000183900 ⚠
Proteasome subunit, putative
— OG7
LAMA_000804800 ⚠
Proteasome subunit, putative
— OG7
LAMA_000295900 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000031800 ⚠
Hsp70 protein, putative
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000498900 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000307500 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000741000
hypothetical protein, conserved
— Both
LAMA_000584700
hypothetical protein, conserved
— Both
LAMA_000504900
hypothetical protein, conserved
— Both
LAMA_000592700
Phosphatidylinositol-specific phospholipase C
— Both
LAMA_000668900 ⚠
Microtubule-binding protein MIP-T3 CH-like do
— Both
LAMA_000660800
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000401000
hypothetical protein, conserved
— Both
LAMA_000409100
WD domain, G-beta repeat, putative
— OG6
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— Both
LAMA_000485800
hypothetical protein, conserved
— Both
LAMA_000140900
BILBO1 N-terminal domain/EF-hand domain pair,
— Both
LAMA_000323000 ⚠
Proteasome subunit, putative
— Both
LAMA_000154200
Paraflagellar rod protein, putative
— Both
LAMA_000210000
KH domain containing protein, putative
— Both
LAMA_000599000
hypothetical protein, conserved
— Both
LAMA_000751700
RNA-binding signal recognition particle 68, p
— Both
LAMA_000468200
hypothetical protein, conserved
— Both
LAMA_000129600
Adaptin N terminal region/non-SMC mitotic con
— Both
LAMA_000428100
LSM domain containing protein, putative
— Both
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.