LAMA_000498900

Elongation factor Tu GTP binding domain/Elongation factor G, domain IV/Elongation factor G C-terminus, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102502 OG7: OG7_0002134 195 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 195 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000246900 ⚠
Aspartate/ornithine carbamoyltransferase, car
— Both
LAMA_000115100 ⚠
Clp amino terminal domain, pathogenicity isla
— Both
LAMA_000040200 ⚠
ATPase family associated with various cellula
— Both
LAMA_000803800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000568000 ⚠
Flavodoxin/FAD binding domain/Oxidoreductase
— OG7
LAMA_000495500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000506300 ⚠
Nucleotidyltransferase domain/RNA editing 3'
— OG7
LAMA_000435100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000657400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000540500 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000219500 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000380900 ⚠
AAA domain (dynein-related subfamily)/Midasin
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000292800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000562800 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000172800 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000814900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000322400 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000416900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000213000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000416000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000530500 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000805000 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
LAMA_000784400 ⚠
Proteasome complex subunit Rpn13 ubiquitin re
— OG7
LAMA_000792100 ⚠
Flavodoxin/FAD binding domain containing prot
— OG7
LAMA_000354300 ⚠
Flavodoxin/FAD binding domain/Oxidoreductase
— OG7
LAMA_000340400 ⚠
Bromodomain, putative
— OG7
LAMA_000376700 ⚠
Bromodomain, putative
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000131800 ⚠
Isochorismatase family, putative
— OG7
LAMA_000184300 ⚠
Isochorismatase family, putative
— OG7
LAMA_000244400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000688200 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000462200 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000512800 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000221800 ⚠
Enolase, N-terminal domain/Enolase, C-termina
— OG7
LAMA_000541800 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
LAMA_000209500 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
LAMA_000448800 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
LAMA_000377000 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
LAMA_000407500 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000408000 ⚠
TCP-1/cpn60 chaperonin family, putative
— +4 more OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.